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Time to death in immunized mouse strains
| Mouse strain | Time to death, days
|
||
|---|---|---|---|
| 103PFU | 102PFU | 101PFU | |
| perf−/− | 8.5 (0.55) | 9.2 (0.41) | 9.5 (0.83) |
| perf×gzmB−/− | 8.5 (0.55) | 9.2 (0.41) | 9.0 (0.63) |
| perf×gzmA×B−/− | 8.3 (0.52) | 9.3 (0.52) | 9.8 (0.41) |
| gzmA×B−/− | 9.6 (0.89) | 13.0 (1.0) | 13.8 (0.45) |
Mice of same sex and age were immunized into the hind footpad with virulent Moscow Ect at the indicated doses. Mean time to death (±SD) is calculated from mice shown in Fig. 1A and D.
