Figure 3.

Expression of low-affinity receptors in macrophages infected with HIV. A dramatic increase of p75^NTR receptor expression was consistently obtained by treating HIV-infected M/M with anti-NGF Ab. An IgG isotypic Ab was totally ineffective. A quantitative analysis of p75^NTR immunoreactive cells (carried out with a computerized image-analysis system) shows a statistically significant increase of p75^NTR immunopositive cells in HIV-infected human M/M treated with anti-NGF Ab compared with all other samples, either infected or not (ANOVA: F(4, 85) = 289.354; P = 0.001).