RNase protection to quantify expression of exons 1B and 2A.
(A) Specific protected fragments of 206 bp (exon 2A/3)
and 135 bp (exon 1B/3) were generated by simultaneous hybridization
of two probes with mouse, but not yeast, RNA. (B) The
signal generated is linearly related to the amount of RNA for both
probes under these conditions, allowing quantitative analysis.
(C) Amount of each transcript present (in arbitrary
units) in 30 μg of total RNA from four different tissues. H, heart;
B, brain; M, muscle; K, kidney.