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. 1999 Nov 23;96(24):14106–14111. doi: 10.1073/pnas.96.24.14106

Figure 2.

Figure 2

Cells expressing Go-VN receptor mRNAs are reduced in number in Go −/− mice. (a) In situ hybridization for two Go-VN receptor transcripts, EC10 and EC11, is illustrated for P15 VNO samples from Go +/+ and −/− samples. Note the reduction in receptor-positive cells in the Go-deficient specimens. (Bar = 50 μm.) (b and c) The number of cells expressing EC10 or EC11 mRNA was measured in the central 200-μm circumferential extent of sections through the mid portion of the VNO. Note the significant reduction in the Go-VN-positive cells in the P15 and P28 Go −/− mice compared with age-matched +/+ mice (*, P ≤ 0.05, Student’s two-tailed t test). The data are means ± SEM from 2–8 animals in each group.