Reduced c-Fos-IR in the mitral cells of the posterior AOB in
Go −/− mice. (a) P15 AOB parasagittal
sections were stained with anti-c-Fos. The following features are
labeled: mitral and tufted cell layer (MT), anterior (Ant), posterior
(Post), and the border of the two AOB lobes (arrowheads). In the
Go −/− sections, the posterior MT layer has fewer
c-Fos-IR nuclei (arrows) than the +/+ sample. The width of the (Post)
label corresponds to 70 μm. (b) The number of c-Fos-IR
mitral cell nuclei was quantitated in mid AOB sections from P8 and P15
mice for the anterior and posterior portions. The number of c-Fos-IR
cells in the posterior AOB is decreased significantly in the
Go −/− mice compared with the number in +/+ control
samples (*, P [ltequ} 0.05, Student’s
two-tailed t test). The data are means ± SEM from
5–8 animals in each group.