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. 1999 Nov 23;96(24):14136–14141. doi: 10.1073/pnas.96.24.14136

Figure 3.

Figure 3

Vasodilator action of Abn-cbd and its antagonism by cannabidiol (CBD) in the rat isolated mesenteric arterial bed. Each panel represents a separate preparation, illustrating the long lasting vasodilation by 4 mg of Abn-cbd (A), and its reversal (B) or prevention (C) by 10 μM CBD. Phenylephrine (PE, 15 μM) used to precontract the preparation and CBD were included in the perfusion buffer, as indicated by the horizontal lines, and the bolus injection of 4 mg of Abn-cbd is indicated by the arrows. These experiments were replicated in 4–6 additional preparations with similar results. (D) Structures of CBD and Abn-cbd.