Table 2.
Olfactory habituation/dishabituation of offspring of WT mothers (VIP +/+) mated to VIP +/− males and VIP deficient mothers (VIP +/−) mated with VIP +/− males. The number of seconds spent sniffing ±SEM of 3, 2 min presentations each of water, odor from Cage 1, and odor from Cage 2 was recorded.
| WT mother | VIP deficient mother | ||||
|---|---|---|---|---|---|
| Offspring genotype | VIP +/+ (n=15) |
VIP +/− (n=13) |
VIP +/+ (n=26) |
VIP+/− (n=49) |
VIP−/− (n=18) |
| Sequence in which applicators were presented: | |||||
| 1st Water | 1.9±0.3 | 2.06±0.4 | 1.5±02 | 1.8±0.2 | 1.5±0.2 |
| 2nd Water | 1.6±0.2 | 1.3±0.2 | 1.1±0.1 | 1.2±0.1 | 1.2±0.2 |
| 3rd Water | 0.9±0.1 | 1.3±0.1 | 0.7±0.1 | 0.9±0.1 | 0.8±0.1 |
| 1st Cage 1 | 7.0±0.7* | 7.3±0.9* | 10.3±0.8*# | 9.5±0.5*# | 9.4±0.7*# |
| 2nd Cage 1 | 2.4±0.5 | 3.2±0.9 | 3.8±0.4 | 3.5±0.3 | 3.3±0.4 |
| 3rd Cage 1 | 1.5±0.3 | 2.0±0.4 | 2.4±0.4 | 2.5±0.3 | 2.2±0.3 |
| 1st Cage 2 | 3.7±0.7* | 3.8±0.7* | 4.5±0.4* | 3.9±0.4* | 3.5±0.4* |
| 2nd Cage 2 | 1.6±0.4 | 1.9±0.3 | 1.8±0.3 | 1.98±0.2 | 2.0±0.3 |
| 3rd Cage 2 | 0.9±0.2 | 1.1±0.3 | 1.1±0.2 | 1.5±0.2 | 1.3±0.2 |
*
= significantly different from time spent sniffing previous applicator, p < 0.05.
#
= significantly different from time VIP +/+ offspring of WT mother spent sniffing 1st applicator with scent from Cage 1, p < 0.05.