Figure 8. Light responses of AII amacrine cells are more amplified than those of rod bipolar cells.
Light responses in the AII amacrine cell more amplified than in the rod bipolar cell. (A) Current responses of a rod bipolar cell to a 10 ms dim flash (gray; 0.06 Rh*/rod) and saturating flash (black; 37.8 Rh*/rod). (B) Current responses of an AII amacrine cell to a 10 msec dim flash (gray; 0.07 Rh*/rod) and saturating flash (black; 4 Rh*/rod). Signals are amplified in the AII amacrine cell. (C) Intensity-response relations for rod bipolars and AII amacrine cells taken from (Dunn et al., 2006) and shown on a scale for photon absorptions per rod bipolar. Flash strength does not account for the nonlinearity at the rod-to-rod bipolar synapse to show effective photon absorptions; this would shift the data points leftward by a factor of 0.3–0.5. AII amacrines cell responses reach saturation at light levels 100 times less than responses of rod bipolar cells.