FIG. 6.

T-cell response to PvTRAg40. SI are given for PBMC from subjects exposed to P. vivax or from malaria-naïve controls. The cells were stimulated with HPLC-purified recombinant PvTRAg40 protein, with the mitogen PHA as a control, or with medium alone as a background control. For calculation, mean scintillation counts per minute were calculated. Open circles represent SI values for control individuals who had no history of malaria exposure (n = 10), and solid circles represent SI values for subjects recently exposed to P. vivax who had recovered 8 to 14 weeks prior to study (n = 20). SI values of >2.0 were considered positive (the cutoff value is shown by the dashed line).