FIG. 6.

Effect of oral administration of A. suum extract (Ascaris) on release of cytokines into the joint cavity in ZYA in mice. Mice received 1 mg of the A. suum extract or saline (−) p.o. 30 min prior to 0.1 mg zymosan i.a. Naive mice received only saline i.a. or saline i.a. plus A. suum extract p.o. IL-1β (A), TNF-α (B), and IL-10 (C) levels were assessed using ELISA (see text for details). Results represent means ± SEM, measured at 6 h (n = 6 animals for each group). Experiments were done two times. *, P < 0.05 compared to control (−) mice.