FIG. 2.

Summary of epithelial cell actin and MAP kinase-related genes differentially regulated (P < 0.005) following infection with the P. gingivalis SerB mutant compared to the parental strain. The pathway was adapted from Pathway Express and utilizes the Kegg nomenclature. Red represents upregulation, green represent downregulation, and gray represents no change in expression. +P indicates phosphorylation; −P indicates dephosphorylation. Pointed arrows indicate molecular interactions resulting in activation; flat arrows indicate molecular interactions resulting in inhibition. Solid lines show a direct interaction, and dotted lines are interactions involving intermediates.