Skip to main content
. 2008 Mar 24;76(6):2568–2575. doi: 10.1128/IAI.00033-08

FIG. 2.

FIG. 2.

Concentration-dependent binding of anti-fHbp MAbs to epitopes on wild-type and chimeric fHbps. The chimera I and II vaccines are identical except for a single amino acid substitution in chimera II (A174K). (A) Binding of MAbs prepared against fHbp v.1. JAR 1 and 5 are specific for v.1 proteins, while JAR 4 cross-reacts with v.1, v.2, and, to a lesser extent, v.3 (44). (B) Binding of MAbs prepared against fHbp v.2. JAR 10 cross-reacts with fHbp v.1, v.2, and v.3 (4), and JAR 11 and 13 cross-react with v.2 and v.3. (C) Binding of MAbs prepared against fHbp v.3. JAR 32 and 36 cross-react with v.2 and v.3.