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. 2008 Mar 24;76(6):2568–2575. doi: 10.1128/IAI.00033-08

FIG. 3.

FIG. 3.

IgG anti-fHbp antibody responses (1/GMT ± 2 SE) of mice (n = 5 per group), measured by ELISA using rfHbp v.1 (gene from strain MC58, top panel) or fHbp v.2 (gene from strain 8047, bottom panel) as the antigen on the plates. Mice immunized with wild-type rfHbp v.1 had a higher anti-rfHbp v.1 reciprocal GMT than mice immunized with fHbp v.2 (P = 0.097). Mice immunized with rfHbp v.2 had a higher anti-fHbp v.2 reciprocal GMT than mice immunized with fHbp v.1 (P = 0.005). There were no significant differences between the respective anti-v.1 antibody responses of mice given the chimera I or II vaccine and those of control mice immunized with the wild-type v.1 protein, and there were no significant differences between the respective anti-v.2 antibody responses of mice given the chimera I or II vaccine and those of control mice immunized with the wild-type v.2 protein.