FIG. 4.
Tp regulate IL-10 and IL-12 production in LPS-treated DC and induce TGF-β production by DC. Cells (106/ml) were incubated in medium or stimulated with LPS (10 μg/ml), Tp at a Tp/cell ratio of 4/1, and Tp+LPS for 24 h. In culture supernatants the IL-10 (A), TGF-β (B), and IL-12p70 (C) levels were determined by ELISA. ND, not detected. The results are represented as the means ± the SEM of seven independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (compared to the respective controls).