TABLE 1.
Genes represented by Pum1-associated mRNA in various GO categories
Analysis method and GO category (positively or negatively enriched) | No. of genes | P value |
---|---|---|
Panther | ||
Positively enriched | ||
mRNA transcription | 100 | 9.66E-04 |
mRNA transcription regulation | 71 | 9.40E-03 |
Transcription factor | 103 | 3.02E-05 |
Other transcription factor | 32 | 4.42E-02 |
Nucleoside, nucleotide, and nucleic acid metabolism | 173 | 2.57E-02 |
Cell proliferation and differentiation | 51 | 1.76E-02 |
Negatively enriched | ||
Oxidoreductase | 5 | 9.90E-07 |
Reductase | 0 | 1.15E-02 |
Dehydrogenase | 2 | 2.85E-02 |
Electron transport | 2 | 1.32E-02 |
WebGestalt | ||
Positively enriched | ||
Regulation of biological processes | 220 | 1.17E-09 |
Regulation of transcription | 138 | 5.48E-10 |
Transcription factor activity | 67 | 1.10E-09 |
Regulation of cell cycle | 42 | 2.71E-03 |
Ubiquitin cycle | 30 | 5.80E-03 |
Wnt receptor signaling pathway | 11 | 1.95E-03 |
Small GTPase-mediated signal transduction | 32 | 3.75E-04 |
Cell communication | 128 | 2.13E-04 |
GSEAa | ||
Positively enriched | ||
UVC high all DN | 117 | <0.001 |
UVB NHEK1 DN | 66 | <0.001 |
CMV/HCMV time course all up | 76 | <0.001 |
HOX genes | 10 | <0.001 |
Cell cycle | 28 | <0.001 |
For GSEA results, the numbers of genes reported represent core enrichment. The GO category names for GSEA are those used in the analysis software.