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Patterns of PrPd accumulation in the brain of clinically affected BSE challenged deer. PrPd immunohistochemical labelling of the vestibular nuclei using Bar 224 antibody shows that the neuropil has severe particulate and linear deposits of PrPd accumulation (brown pigment denotes PrPd). There is also marked intraneuronal labelling present (arrow). Bar = 100 μm.
