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. Author manuscript; available in PMC: 2009 May 6.
Published in final edited form as: Eur J Pharmacol. 2008 Feb 26;585(1):64–75. doi: 10.1016/j.ejphar.2008.02.050

Table 1.

Plasma endocrine analysis following DHEA administration

Plasma endocrine measure Control STZ + Chow STZ + DHEA
Glucose (mg/dl) 124.2 ± 3.2 489.3 ± 20.6a 444.3 ± 21.7a
Insulin (ng/ml) 0.437 ± 0.16 0.034 ± 0.018a 0.037 ± 0.03a
DHEA-SO4 (ug/dl) 0.00 0.00 75.8 ± 19.5a/b
Corticosterone (ug/dl) 3.39 ± 0.43 2.19 ± 0.42 3.89 ± 0.63

Rats were provided standard chow (control and STZ + Chow) or standard chow supplemented with 0.4% DHEA (STZ + DHEA). Fasting glucose levels were measured by glucose-trinder assay; insulin, DHEA-SO4 and corticosterone were measured by radioimmunoassay.

a

= significantly different from control;

b

= significantly different from STZ + Chow.

*

/# = p = 0.001.