Table 1.
Center | Population | Persons Tested, n | Men, % | Mean Age (SD), y | Breast Cancer, n | Ovarian Cancer, n | No Cancer, n | BRCA1 Positive, n | BRCA2 Positive, n | Reference |
---|---|---|---|---|---|---|---|---|---|---|
BCM | Ashkenazi Jewish volunteers | 282 | 0 | 53.1 (11.8) | 33 | 2 | 247 | 6 | 0 | 25 |
City of Hope | Counseling clinic | 77 | 0 | 49.8 (13.0) | 47 | 5 | 25 | 13 | 5 | 26 |
Duke University | Counseling clinic | 275 | 0 | 47.8 (10.7) | 237 | 27 | 22 | 41 | 18 | 27 |
FHCRC | Population-based study | 583 | 0 | 45.7 (5.1) | 320 | 6 | 263 | 22 | 12 | 28 |
Georgetown University | Counseling clinic | 242 | 0 | 52.9 (11.4) | 227 | 20 | 3 | 55 | 23 | 21 |
HCI | Counseling clinic | 61 | 0 | 58.5 (15.2) | 47 | 2 | 12 | 6 | 8 | - |
JHU | Counseling clinic | 105 | 3 | 50.2 (10.3) | 57 | 7 | 43 | 0 | 6 | 29 |
Penn | Counseling clinic | 676 | 69 | 50.9 (13.0) | 489 | 82 | 138 | 121 | 53 | 11, 30 |
UTSW | Counseling clinic | 121 | 7 | 47.9 (12.8) | 67 | 10 | 50 | 23 | 9 | 24 |
UCI | Population-based study | 803 | 9 | 62.5 (13.6) | 605 | 122 | 87 | 10 | 4 | 31 |
MDACC | Counseling clinic | 117 | 7 | 51.2 (13.3) | 59 | 8 | 53 | 25 | 18 | 32 |
Total | - | 3342 | 95 | 52.8 (13.1) | 2188 | 291 | 943 | 332 | 156 | - |
BCM = Baylor College of Medicine; FHCRC = Fred Hutchinson Cancer Research Center; HCI = Huntsman Cancer Institute; JHU = Johns Hopkins University; MDACC = M.D. Anderson Cancer Center; Penn = University of Pennsylvania; UCI = University of California, Irvine (Orange County); UTSW = University of Texas Southwestern.