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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Horm Behav. 2007 Nov 28;53(5):596–612. doi: 10.1016/j.yhbeh.2007.11.008

Figure 3.

Figure 3

Digital micrographs of thionin-stained SNB somata in a normal adult male (A), a castrate (B), and a castrate treated with testosterone (C), demonstrating the androgen sensitivity of soma size in adulthood. (D) Testosterone increases SNB soma size only in cells expressing the wild-type (WT) androgen receptor (AR). Adult female carriers of the Tfm mutation were implanted with blank capsules or capsules filled with testosterone. SNB soma size was assessed 4–6 weeks later. Some SNB motoneurons in these females express the WT AR, whereas others express the non-functional, Tfm AR. Only SNB motoneurons expressing the WT AR responded to testosterone with an increase in soma size. (Panels A–C, D.R. Sengelaub; Panel D reprinted from Watson et al., (2001) with permission from the Society for Neuroscience.)