TABLE 1.

Sequences of the human PATE-like and mouse Pate-like proteins and signal peptide prediction

The amino acid sequences of the human PATE-like (and mouse Pate-like) proteins are presented starting with the initiating methionine. Upper panel, sequences were subjected to SignalP analysis-signal peptide probabilities, and the predicted signal peptide cleavage sites are presented. The upward facing arrow designates the predicted cleavage site of the signal peptide, and the red dots indicate the exon boundaries. Hydrophobic amino acid residues downstream to the initiating methionine, and likely comprising the signal peptide, are highlighted. Lower panel, exons 2 and 3 include cysteines 1-5 and cysteines 6-10, respectively.