Fig. 1.
Effects of a single MK-886 injection on mouse behavior in the forced swimming test. Mice (n = 6) received i.p. injections of 3 and 10 mg/kg MK-886 or vehicle 30 min prior to testing. Results are shown as mean ± S.E.M.; open bars = vehicle (Veh), closed bars = MK-886 (MK). (A) basic movements, (B) climbing, (C) rest time. There were no significant differences between drug treated groups and vehicle treated controls.