TABLE 1.

Summary of 11β-HSD2 promoter deletion analysis results obtained with T47D-YV and T47D cells^a

Cell type and overexpressed isoform	11β-HSD2 promoter region	Fold induction	Range
T47D-YV	−1778/+117	1.51	±0.10
PRB	−1778/+117	11.41	±0.21
	−1778/+1	10.38	±0.34
	−1551/+117	8.66	±0.02
	−839/+117	1.26	±0.01
	−571/+117	1.10	±0.01
	−368/+117	1.12	±0.02
PRA	−1778/+117	8.07	±1.54
	−1778/+1	9.25	±0.44
	−1551/+117	6.57	±0.03
	−839/+117	1.35	±0.03
	−571/+117	1.13	±0.03
	−368/+117	1.07	±0.01
T47D	−1778/+117	3.15	±0.11
	−1778/+1	2.92	±0.07
	−839/+117	1.66	±0.20
	−571/+117	1.53	±0.10
	−368/+117	1.53	±0.07
PRB	−1778/+117	12.24	±0.77
	−1778/+1	13.43	±0.51
	−1551/+117	5.49	±0.29
	−839/+117	2.70	±0.79
	−571/+117	3.28	±0.17
	−368/+117	3.05	±0.36
PRA	−1778/+117	8.68	±0.21
	−1778/+1	7.95	±0.51
	−839/+117	1.38	±0.48
	−571/+117	2.09	±0.06
	−368/+117	1.59	±0.26

^aThe average induction levels and ranges of Luc activity for hormone/vehicle from two independent experiments performed in duplicate are shown.