Table 2.
Percent Variation Due to oim Mutation and Genetic Background
Outbred | B6 | |||
---|---|---|---|---|
Geometry | oim | Genetic | oim | Genetic |
Mutation | Background | Mutation | Background | |
Body Mass | 36% | 64% | 45% | 55% |
Femur Length | 27% | 73% | 11% | 89% |
Marrow Cavity Diameter | 52% | 48% | 24% | 76% |
Cortical Bone Width | 11% | 89% | 6% | 94% |
Polar Moment of Area | 55% | 45% | 32% | 68% |
Biomechanics | oim | Genetic | oim | Genetic |
Mutation | Background | Mutation | Background | |
Tmax | 67% | 33% | 52% | 48% |
Su | 36% | 64% | 56% | 44% |
Ks | 28% | 72% | 9% | 91% |
G | <5% | >95% | <5% | >95% |
U | 52% | 48% | 54% | 46% |
Collagen and Mineral; | oim | Genetic | oim | Genetic |
Bone Turnover | Mutation | Background | Mutation | Background |
F, Mg and Na Content | 41–56%a | 44–59%a | 69–71%a | 29–31%a |
Hydroxyproline | 37% | 63% | 37% | 63% |
Pyridinoline Crosslinks | <5% | >95% | <5% | >95% |
Exact percentage is mineral specific.