Skip to main content
. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2007 Sep 5;226(3):213–224. doi: 10.1016/j.taap.2007.08.024

Fig. 11.

Fig. 11

Effects of BKF and metabolites on CYP1A1 promoter activity in T-47D cells. Cultures were co-transfected with the pHu-1A1-FL and pRL-CMV Renilla luciferase vectors for 24 h, followed by 18-h exposure to the indicated concentrations of the BKF metabolites, BKF, and BAP. Cells were lysed, firefly and Renilla luciferase activities were measured and the ratios of firefly to Renilla activities were determined as relative luciferase activity. Values shown are the mean ± SE of triplicate determinations.