Skip to main content
. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2008 Feb 13;44(4):654–661. doi: 10.1016/j.yjmcc.2008.01.010

Figure 1.

Figure 1

Schematic model of autophagy. Induction of autophagy starts with the formation of the initial isolation membrane or phagophore and the subsequent recruitment of essential Atg proteins to start the elongation of the membrane. The membrane surrounds proteins or organelles in the cytosol to be sequestered and then fuses with the lysosome to form the autolysosome where the content is degraded.