RT-PCR analysis of steroidogenic enzymes in cultured 1°MG. A–D) 1°MG cells were stimulated for 24hr with 100ng/ml LPS+ 10ng/ml INFγ (LPS), 10ng/ml INFγ (INFγ), LPS-conditioned media (LCM), 1mM db-cAMP (db-cAMP), or vehicle (Veh) (hatched bars). Bars represent the % expression of each enzyme with respect to vehicle and normalized to the housekeeping gene L27A. Values are the mean ± the SEM of 2–3 independent experiments done in triplicate. *, **, P < 0.05, P < 0.001 vs. Veh, respectively.