Table 1.
Kinetic parameters for recombinant GR2
Varied substrate | Chemical structure of varied substrate | Fixed substrate | Km (mM) | Vmax (μmol min−1 mg−1 protein) | kcat (s−1) | kcat/Km (s−1 mM−1) |
Glyoxylate | ![]() |
NADPH | 0.034±0.003 | 40.6±8.7 | 22.5±4.8 | 660±130 |
NADPH | Glyoxylate | 0.0014±0.0002 | 23.0±2.2 | 12.0±0.8 | 8550±960 | |
SSA | ![]() |
NADPH | 8.96±0.71 | 30.7±4.0 | 17.0±2.2 | 1.89±0.27 |
NADPH | SSA | 0.0012±0.0002 | 19.3±1.5 | 10.7±0.8 | 9180±1620 |
Kinetic data for varied substrate concentrations were best fit by non-linear regression analysis. Parameters represent the mean ±SE of three independent enzyme preparations.