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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Psychopharmacology (Berl). 2007 Sep 17;195(4):469ā€“478. doi: 10.1007/s00213-007-0923-8

Figure 2.

Figure 2

Sensitization to AMPH- and METH-induced locomotion (A) and rearing (B), represented as the difference between activity during the 60-min period following the challenge (day 11) and acute (day 2) injections (n = 8 rats/group). Statistical analysis, which was performed on the raw data from the two injection days (see Results), revealed statistically significant sensitization for locomotion in all groups except the 0.5 mg/kg METH, Sāˆ’ group; sensitization to drug-induced rearing was only evident in the 0.5 mg/kg AMPH, S+ and the 1.0 mg/kg METH, S+ groups. The only significant difference in the magnitude of sensitization was between the 0.5 and 1.0 mg/kg dose of METH in the absence of the stimuli (Sāˆ’). * p < 0.05