Table 4.

Factors Associated with Lipids and CRP Among HIV-Infected Men

Total cholesterol, mg/dL				LDL-C, mg/dL
Parameter	Regression coefficient	95% CI	p	Parameter	Regression coefficient	95% CI	p
HCV-infected	−33.69	−49.20--18.18	<0.001	HCV-infected	−23.18	−35.55--10.81	<0.001
PI-HAARTa	15.16	−3.86−34.18	0.12	PI-HAARTa	0.12	−15.05−15.29	0.98
Non-PI-HAARTa	−3.32	−27.18−20.54	0.78	Non-PI-HAARTa	−2.74	−21.77−16.30	0.78
Detectable HIV-1 viral loadb	−16.72	−32.68--0.75	0.04	Detectable HIV-1 viral loadb	−12.07	−24.68−0.66	0.06
Age ≥ mediana	6.04	−8.88−20.97	0.42	Age ≥ mediana	11.10	−0.81−23.0	0.07
log10 (HOMA-IR)b	10.83	−8.92−30.59	0.28	log10 (HOMA-IR)b	15.33	−4.29−31.09	0.06
High fiber, low fat dietary intake	−17.13	−34.17−0.09	0.049	High fiber, low fat dietary intake	−6.82	−20.42−6.77	0.32
log10 (triglycerides), mg/dLa				log10 (CRP), mg/dLa
HCV-infected	0.14	−0.06−0.3	0.18	HCV-infected	−0.39	−0.65--0.13	0.004
PI-HAARTa	0.34	0.14−0.54	0.001	PI-HAARTa	−0.09	−0.22−0.40	0.57
Non-PI-HAARTa	0.18	−0.05−0.41	0.13	Non-PI-HAARTa	−0.03	−0.43−0.36	0.88
(HCV status) × (PI)	−0.29	−0.52--0.05	0.02	Detectable HIV-1 viral loadb	0.07	−0.20−0.32	0.50
(HCV status) × (Non-PI)	−0.34	−0.62--0.06	0.02	Age ≥ medianc	−0.05	−0.29−0.20	0.70
Detectable HIV-1 viral loadb	0.04	−0.05−0.14	0.34	Waist circumference	0.01	−0.001−0.02	0.07
Age ≥ medianc	−0.06	−0.15−0.03	0.17	Pack-years of smoking	0.007	0.000−0.01	0.05
log10 (HOMA-IR)d	0.12	0.000−0.24	0.049
High fiber, low fat dietary intake	−0.05	−0.15−0.06	0.37

^aReference group: ARV-naïve HIV-infected men.

^bDetectable HIV-1 viral load indicates HIV-1 viral load ≥75 copies/mL.

^cMedian age = 54 years.

^dInsulin resistance as measured by homeostasis model assessment (HOMA-IR), triglycerides, and C-reactive protein were log-transformed to meet normality criteria for linear regression.

Waist circumference measured in cm, HOMA-IR in U/mL · mmol/L.

CRP, C-reactive protein; LDL-C, low-density lipoprotein cholesterol; PI, protease inhibitor; HAART, highly active antiretroviral therapy.