Figure 1. Hierarchical clustering analysis of gene alterations following Trsp removal in liver.

Hierarchical dendrogram representing the expression profiles of significantly altered genes, following data filtering as described in Results. (A) upregulated or (B) downregulated in knockout mice. The genes are ordered by clustering tightness, with a distance measure of 1 - Pearson correlation coefficient and a P-value threshold of 0.05. Each column represents data from one experimental set, and rows indicate individual genes. Increases and decreases in transcript expression levels are represented by shades of red and green, respectively.