Table 1.
Summary of mouse lines, their genotypes and designations
| Mice | Genotype | Designation f |
|---|---|---|
| Wild type a | Trsp+/+-AlbCre+/+ | Trsp |
| Trsp liver knockout b | Trspfl/fl-AlbCre+/+ | ΔTrsp |
| A34 transgenic (2 copies) c | Trspfl/fl-AlbCre+/+-A34t/t | A34 |
| G37 transgenic (2 copies) d | Trspfl/fl-AlbCre+/+-G37t/t | G37L |
| G37 transgenic (16 copies) e | Trspfl/fl-AlbCre+/+-G37t/t | G37H |
a
Wild type mice were homozygous for Trsp and albumin Cre.
b
Trsp liver knockout mice lacked Trsp in their liver.
c
A34 transgenic mice carrying 2 copies of the T34→A34 mutant transgene.
d
G37 transgenic mice carrying 2 copies of the A37→G37 mutant transgene.
e
G37 transgenic mice carrying 16 copies of the A37→G37 mutant transgene.
f
Designations used in the text to denote each mouse line.