Figure 5.
Association of ATR-ATRIP with O6-meG/T Requires Both MutSα and MutLα Recovery of ATR and ATRIP at O6-meG/T-containing DNA was determined in the CrIP assay by using LoVo or HCT116 nuclear extracts either alone or supplemented with purified, recombinant murine MutSα or MutLα as indicated. Error bars represent the SDs of three independent experiments.