Table 1.
D155931 (μM)a |
D157070 (μM)a |
|||
---|---|---|---|---|
Condition | BCG | Mtb | BCG | Mtb |
7H9, pH 6.6 | NE | NE | NE | NE |
7H9, pH 6.6 + DETANO | - | - | 1 | - |
7H9, pH 5.5 | 10 | NE | 15 | NE |
7H9, pH 5.5 + NO2− | 3 | 15 | 2 | 10 |
DMEM-10%FBS, pH 7.4 | - | - | 4 | >10 |
Hypoxia, NRP-2 | - | - | - | 25 |
Mouse BMMs | NE | NE | 5 | 5 |
-, not tested; NE, no effect.
Concentration at which 2 log10 killing is observed.