Figure 1.
Characteristic clinical features of fibrodysplasia ossificans progressive (FOP). (a) Extensive heterotopic bone formation typical of FOP is seen by three-dimensional reconstructed computed tomography scan of the back of a 12-year-old child. (b) Anteroposterior radiograph of the feet of a 3-year-old child shows symmetrical great toe malformations. Source: Shore et al. Nature Genet 2006; 38: 525–527. Copyright held by the authors.