Table 2.
Anticonvulsant drugs used at the National Hospital (Queen Square) in London, before and after the clinical introduction of phenobarbital in the treatment of epilepsy
| 1910 | 1930 | ||
|---|---|---|---|
| Drugs of definite benefit | Drugs of doubtful benefit | Drugs of definite benefit | Drugs of doubtful benefit |
| Bromides | Monobromate of camphor | Bromides | Zinc salts |
| Chloral hydrate | Eosinate of sodium | Bromide combinations | Iron |
| Glycerophosphates | Chloretone | Phenobarbital | Digitalis |
| Borax | Antipyrin | Borax | Strophanthus |
| Belladonna | Double tartrate of | Calcium | |
| Zinc salts | borax and potassium | Opiates | |
| Opium | Belladonna | Hypnotics | |
| Strychnine | Nitroglycerine | ||
| Chloride of calcium | |||
| Atropine | |||
Adapted from Shorvon and Sander (1996).