Table 1.

Comparison of 17 214 GOOD human/mouse orthologous pairs with the four existing ortholog databases

	GOOD	HomoloGene	UCSC known genes	Ensembl compara	Inparanoid
# Reference Sequence	N/A	16 325 HIDa	14 692 kgIDb	22 047	15 549
# Region-based Orthologous Pairs	17 214	14 843	12 111	12 362	9023
# Region-based Orthologous Pairs also identified by GOOD	N/A	14 327	11 889	11 332	8825
Human reference gene coverage rate	∼80%	∼69%	∼56%	∼57%	∼42%

^aHID: HomoloGene group id.

^bkgID: Human/Mouse reciprocal conserved UCSC Known Genes ID pair.

N/A: not applicable.

HomoloGene: build 56

UCSC Known Genes: hg18/mm8

Ensembl Compara: release 46

Inparanoid: version 5.1

There are 21 544 human regions from the RefSeq (NCBI build 36). There might be some loss when transforming ids among different databases.

Compared to current ortholog databases, GOOD has higher consistency and also provides the highest coverage rate of the human genome.