Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Parameter transformations change the action potential shape and the spiking frequency in a predictable way. We simulated a spiking neuron having one m4h Nav and one n4 Kv channel types (black line in each graph), then we applied several transformations to the parameters of the Nav model (rate factors) (A–D), and to the Na conductance (E), Na reversal voltage (F), and injected offset current (G), as indicated (red and blue lines).
