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Nonchannel conformer population for single-tryptophan gramicidin analogs in lipid vesicles based on size-exclusion chromatography
| Gramicidin analog | DMPC | POPC |
|---|---|---|
| W(11,13,15)BgA | 5% | 12% |
| W(9,13,15)BgA | 21% | 32% |
| W(9,11,15)BgA | 37% | 32% |
| W(9,11,13)BgA | 43% | 48% |
The percentage of gramicidin analog present in double-stranded (nonchannel) conformation is listed. The peptide/lipid ratio was 1:50 (mol/mol) in all cases. See Materials and Methods for other details.
