Table 4. Statistical analysis of clinical parameters between anti-EsteD positive and negative patients of Vogt-Koyanagi-Harada disease.
Parameter |
P (n=4) |
N (n=12) |
p value |
Age (year) |
35.8±12.7 |
42.1±10.3 |
0.41a |
Sex (M:F) |
0:4 |
8:4 |
0.04b |
HLA-DR4 |
75% (n=4) |
77.8% (n=9) |
0.91b |
LogVA |
-0.49±0.61 |
-0.42±0.21 |
0.84a |
IgG (mg/ml) | 11.6±2.1 | 10.1±3.7 | 0.46a |
Four anti-EsteD antibody positive Vogt-Koyanagi-Harada (VKH) patients and 12 anti-EsteD antibody negative VKH patients were statistically compared their age, sex, Log visual acuity (VA), and serum concentration of total IgG. For the analysis of HLA-DR4, four anti-EsteD antibody positive and 9 anti-EsteD antibody negative VKH patients were analysed. Age, LogVA, and serum IgG concentration were compared by Student’s t test, and sex and the presence of HLA-DR4 were compared by Fisher’s exact probability test. Anti-EsteD antibody positive VKH patients were all female and it was statistically significant compared to anti-EsteD antibody negative VKH patients. There was no statistical difference in other examined factors. aStudent’s t test; bFisher’s exact probability test.