Table 3.
Multivariate linear regression analysis of factors independently associated with bone mineral density of the hip or spine among HIV-infected men.
| Characteristic | Femoral neck (β-coefficient)a | P-value | Lumbar spine (β-coefficient)a | P-value |
|---|---|---|---|---|
| Age (per year) | −0.0001 | NS | 0.006 | 0.03 |
| Non-black race | −0.018 | 0.004 | −0.06 | 0.02 |
| Weight (per kg)b | 0.003 | < 0.0001 | 0.003 | 0.002 |
| Low testosterone | −0.02 | NS | −0.075 | 0.002 |
| HIV infection > 10 years | −0.004 | NS | −0.075 | 0.003 |
| Duration of antiretroviral use (months) | −0.0004 | NS | 0.0001 | NS |
| Duration of protease inhibitor use (months) | 0.0006 | NS | 0.0003 | NS |
| CD4 cell count < 200 cells/μl | 0.003 | NS | −0.03 | NS |
β-coefficients less than zero indicate an inverse association between the characteristic and bone mineral density.
Substitution of body mass index (kg/m2) for weight (kg) did not significantly alter the results of either model, nor alter the β-coefficients or P-values of the other variables in either model.