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. Author manuscript; available in PMC: 2009 May 12.
Published in final edited form as: Vaccine. 2008 Mar 27;26(20):2521–2527. doi: 10.1016/j.vaccine.2008.03.005

Figure 1.

Figure 1

Comparison of antigen specific antibody responses in mice immunized with Alhydrogel formulations with or without the addition of CPG 7909. A. Mice were immunized with the AMA1-rEPA F1 (F1), AMA1-rEPA F2 (F2), AMA1-rEPA F3 (F3) or unconjugated AMA1 (AMA1) formulated on Alhydrogel with (black bars) or without (white bars) the addition of CPG 7909 at a dose of 0.03 μg of AMA1. B. Mice immunized with the Pfs25-rEPA F1 (F1), Pfs25-rEPA F2 (F2) and unconjugated Pfs25 (Pfs25) formulated on Alhydrogel with (black bars) or without (white bars) CPG 7909 at the dose of 0.25 μg of Pfs25. All ELISA results are presented as units compared to the anti-AMA1-FVO or Pfs25 mouse reference standards. Results are expressed as arithmetic mean of ELISA units of the group with each animal represented by an open circle. The asterisks indicate that the antigen specific antibodies are significantly higher for AMA1- or Pfs25-rEPA formulated on Alhydrogel with CPG 7909 than without CPG 7909.