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. Author manuscript; available in PMC: 2009 May 12.
Published in final edited form as: Vaccine. 2008 Mar 27;26(20):2521–2527. doi: 10.1016/j.vaccine.2008.03.005

Table 2.

Transmission blocking assay with anti-Pfs25 antibodiesa

Pfs25-rEPA F1/Alhydrogel
Pfs25-rEPA F1/Alhydrogel + CPG 7909
Sample Dilution 1: 4.4 1: 8.8 1: 17.6 1: 35.2 1: 4.4 1: 8.8 1: 17.6 1: 35.2
ELISA Units in the Feeder 2600 1300 650 325 2600 1300 650 325
% Oocyst Reduction 99% 95% 83% 53% 98% 90% 80% 68%
a

Mouse sera from the groups immunized with Pfs25-rEPA F1/Alhydrogel with and without CPG 7909 at the 0.25 μg dose were pooled, respectively. The ELISA units of the pooled sera were measured and adjusted with naïve mouse sera to give the same initial values before the sera were tested in four 2-fold serial dilutions with naïve human sera in the assay.