Table III. Global recombination frequencies as determined by SCE events in the indicated genotypes.
| Recombination frequency per chromosome |
Mouse genome (kb) | DNA per mouse chromosomea | SCE per kb | |
|---|---|---|---|---|
| Dnmt wt p13 | 0.106 | 3,000,000 | 150,000 | 7.06 × 10−7 |
| Dnmt1−/− p13 | 0.115 | 3,000,000 | 150,000 | 7.66 × 10−7 |
| Dnmt3a,3b−/−p8 | 0.134 | 3,000,000 | 150,000 | 8.93 × 10−7 |
| Dnmt3a,3b−/−p24 | 0.122 | 3,000,000 | 150,000 | 8.13 × 10−7 |
p, passage number.
a
The 150,000 value corresponds to the size of the mouse genome divided by the number of chromosomes multiplied by two diploid cells (300,000 kb/40 × 2 = 150 kb).