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. Author manuscript; available in PMC: 2008 Jun 12.
Published in final edited form as: J Heart Lung Transplant. 2008 May;27(5):554–560. doi: 10.1016/j.healun.2008.01.025

Figure 1.

Figure 1

Vector dose-response in AAV9-CMV-lacZ transduction to the transplanted heart using ex vivo perfusion (0,2×109, 2×1010, 2×1011 and 2×1012 vg/ml). The transplanted heart was explanted 10 days after procedure and stained with X-gal and light hematoxylin. (A) A representative result is shown. Scale bar represents 100um. (B) The percentage of transduced cardiomyocytes. A strong positive correlation was observed between transduction efficiency and the vector dose (the Spearman Correlation Coefficient = 0.9864, p-value <.0001). (C) Total β-galactosidase level. The similar positive correlation was observed between β-galactosidase expression and vector dose (the Spea man Correlation Coefficient = 0.9493, p-value <.0001). Values are means ± standard deviation.