TABLE 2.
Parameter | Overall (n = 40) | Sodium >136 mEq/L (n = 27) | Sodium ⩽ 136 mEq/L (n = 13) | P Value |
---|---|---|---|---|
Hemodynamics | ||||
Heart rate, beats/min | 83 (15) | 77 (11) | 94 (14) | 0.0002 |
SBP, mm Hg | 121 (18) | 124 (20) | 113 (15) | 0.07 |
DBP, mm Hg | 70 (10) | 70 (10) | 71 (11) | 0.82 |
RAP, mm Hg | 11 (5) | 9 (3) | 14 (6) | 0.0004 |
, mm Hg | 48 (11) | 47 (12) | 49 (10) | 0.60 |
Cardiac index, L/min/m2 | 2.2 (0.6) | 2.4 (0.6) | 2.0 (0.6) | 0.05 |
SVI, ml/m2 | 28 (10) | 32 (10) | 21 (7) | 0.002 |
RVSWI, g-m/m2 | 14.3 (6.5) | 16.4 (6.4) | 10.0 (4.2) | 0.002 |
PVRI | 1,463 (700) | 1,327 (597) | 1,744 (832) | 0.08 |
SV/PP, ml/mm Hg | 1.10 (0.49) | 1.21 (0.56) | 0.85 (0.29) | 0.02 |
PCWP, mm Hg | 11 (3) | 11 (3) | 11 (5) | 0.74 |
SvO2, % | 63 (9) | 67 (7) | 54 (9) | 0.000 |
Echocardiography | ||||
TAPSE, cm | 1.8 (0.3) | 2.0 (0.6) | 1.4 (0.3) | 0.001 |
RVFAC, % | 27.8 (9.8) | 30.1 (10.2) | 22.8 (6.4) | 0.03 |
RAAI, cm2/m | 14.8 (5.1) | 13.3 (4.6) | 18.3 (4.8) | 0.003 |
RVAI, cm2/m | 15.5 (3.6) | 14.4 (3.0) | 18.1 (3.7) | 0.003 |
TR, grade 0–4 | 1.97 (0.93) | 1.67 (0.16) | 2.67 (0.22) | 0.001 |
RA:LA dimension | 1.47 (0.41) | 1.37 (0.35) | 1.68 (0.47) | 0.03 |
RV:LV area | 1.45 (0.48) | 1.29 (0.42) | 1.81 (0.42) | 0.0008 |
LV dimension, cm | 3.9 (0.8) | 4.2 (0.6) | 3.3 (0.8) | 0.0002 |
RVSP, mm Hg | 78 (18) | 79 (20) | 75 (14) | 0.60 |
Pericardial effusion, n (%) | 12 (41) | 6 (22) | 6 (50) | 0.03 |
Definition of abbreviations: DBP = diastolic blood pressure; PCWP = pulmonary capillary wedge pressure; = mean pulmonary artery pressure; PVRI = pulmonary vascular resistance index; RAAI = right atrial area index; RA:LA dimension = ratio of right atrial to left atrial dimensions; RAP = right atrial pressure; RVAI = right ventricular area index; RVFAC = right ventricular fractional area change; RV:LV area = ratio of right ventricular to left ventricular area; ; RVSP = right ventricular systolic pressure; RVSWI = right ventricular stroke work index; SBP = systolic blood pressure; SVI = stroke volume index; SvO2 = mixed venous oxygen saturation; SV/PP = ratio of stroke volume to pulmonary artery pulse pressure; TAPSE = triscuspid annular plane systolic excursion; TR = tricuspid regurgitation.
Hemodynamic and echocardiographic data for patients in the overall cohort, and subgroups with a serum sodium >136 mEq/L or ⩽136 mEq/L. Values are expressed as mean (SD).