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. 2008 Mar 20;177(12):1364–1369. doi: 10.1164/rccm.200712-1876OC

TABLE 2.

HEMODYNAMICS AND ECHOCARDIOGRAPHIC MEASUREMENTS

Parameter Overall (n = 40) Sodium >136 mEq/L (n = 27) Sodium ⩽ 136 mEq/L (n = 13) P Value
Hemodynamics
 Heart rate, beats/min 83 (15) 77 (11) 94 (14) 0.0002
 SBP, mm Hg 121 (18) 124 (20) 113 (15) 0.07
 DBP, mm Hg 70 (10) 70 (10) 71 (11) 0.82
 RAP, mm Hg 11 (5) 9 (3) 14 (6) 0.0004
Inline graphic, mm Hg 48 (11) 47 (12) 49 (10) 0.60
 Cardiac index, L/min/m2 2.2 (0.6) 2.4 (0.6) 2.0 (0.6) 0.05
 SVI, ml/m2 28 (10) 32 (10) 21 (7) 0.002
 RVSWI, g-m/m2 14.3 (6.5) 16.4 (6.4) 10.0 (4.2) 0.002
 PVRI 1,463 (700) 1,327 (597) 1,744 (832) 0.08
 SV/PP, ml/mm Hg 1.10 (0.49) 1.21 (0.56) 0.85 (0.29) 0.02
 PCWP, mm Hg 11 (3) 11 (3) 11 (5) 0.74
 SvO2, % 63 (9) 67 (7) 54 (9) 0.000
Echocardiography
 TAPSE, cm 1.8 (0.3) 2.0 (0.6) 1.4 (0.3) 0.001
 RVFAC, % 27.8 (9.8) 30.1 (10.2) 22.8 (6.4) 0.03
 RAAI, cm2/m 14.8 (5.1) 13.3 (4.6) 18.3 (4.8) 0.003
 RVAI, cm2/m 15.5 (3.6) 14.4 (3.0) 18.1 (3.7) 0.003
 TR, grade 0–4 1.97 (0.93) 1.67 (0.16) 2.67 (0.22) 0.001
 RA:LA dimension 1.47 (0.41) 1.37 (0.35) 1.68 (0.47) 0.03
 RV:LV area 1.45 (0.48) 1.29 (0.42) 1.81 (0.42) 0.0008
 LV dimension, cm 3.9 (0.8) 4.2 (0.6) 3.3 (0.8) 0.0002
 RVSP, mm Hg 78 (18) 79 (20) 75 (14) 0.60
 Pericardial effusion, n (%) 12 (41) 6 (22) 6 (50) 0.03

Definition of abbreviations: DBP = diastolic blood pressure; PCWP = pulmonary capillary wedge pressure; Inline graphic = mean pulmonary artery pressure; PVRI = pulmonary vascular resistance index; RAAI = right atrial area index; RA:LA dimension = ratio of right atrial to left atrial dimensions; RAP = right atrial pressure; RVAI = right ventricular area index; RVFAC = right ventricular fractional area change; RV:LV area = ratio of right ventricular to left ventricular area; ; RVSP = right ventricular systolic pressure; RVSWI = right ventricular stroke work index; SBP = systolic blood pressure; SVI = stroke volume index; SvO2 = mixed venous oxygen saturation; SV/PP = ratio of stroke volume to pulmonary artery pulse pressure; TAPSE = triscuspid annular plane systolic excursion; TR = tricuspid regurgitation.

Hemodynamic and echocardiographic data for patients in the overall cohort, and subgroups with a serum sodium >136 mEq/L or ⩽136 mEq/L. Values are expressed as mean (SD).