Table 1.
Comparison of DY547-labeled NTC siRNA tissue uptake based on fluorescent intensity at 4h as compared to control treated tissues.
IV-Hydro | IV-Std. | IP | PR | |
---|---|---|---|---|
Liver | ++ | + | + | − |
Spleen | +++ | ++ | +++ | + |
Pancreas | + | + | − | − |
Kidney | ++ | ++ | − | − |
Bone Marrow | ++ | + | + | + |
Adrenal gland | + | + | − | − |
(− = Absent uptake; + = ≥1.5 – 2 fold change as compared to control; ++ = ≥2 – 3 fold change; +++ = ≥3 fold change)