Table 2.
Comparison of DY547-labeled NTC siRNA tissue uptake based on fluorescent intensity at 24h as compared to control treated tissues.
IV-Hydro | IV-Std. | IP | PR | |
---|---|---|---|---|
Liver | ++ | ++ | + | + |
Spleen | +++ | ++ | ++ | ++ |
Pancreas | − | − | − | − |
Kidney | ++ | + | − | − |
Bone Marrow | + | + | + | + |
(− = Absent uptake; + = ≥1.5 – 2 fold change as compared to control; ++ = ≥2 – 3 fold change; +++ = ≥3 fold change)