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. 2008 Jun 25;3(6):e2496. doi: 10.1371/journal.pone.0002496

Table 7. Immunosuppressant Therapeutic Trough levels used in “High” dose for transplantation rejection and “Low” dose in “Inflammatory” Diseases.

Medication Targeted Trough levels (ng/ml)
“High” level for Organ Transplant Rejection “Low” level in “Inflammatory” Diseases
ng/ml Citation ng/ml Citation
Cyclosporine A 100–400 [63] 70–130 [14]
396 [64] 100–200 [12]
350–400 [65]
Tacrolimus (FK 506) 5–20 [63] 4–8 [67]
17–18 [66] 5–10 [68]
Rapamycin 5–15 [63] No data available (PubMed)