Figure 2.

FDR-Significant DNA-Methylation Differences Associated with Major Psychosis

A positive fold change (red) corresponds to lower DNA methylation in the affected group, and a negative fold change (blue) corresponds to higher DNA methylation in the affected group. Also shown are gene-expression data from the same group of samples obtained from the Stanley Research Foundation database. Dark yellow/green corresponds to significant transcript up-/downregulation in a meta-analysis of all expression studies performed on these samples, and light yellow/green corresponds to evidence of significant up-/downregulation from at least one study. Orange indicates that expression has been reported as altered in both directions in different studies. Grey denotes missing data.