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. 2008 Feb 1;82(2):375–385. doi: 10.1016/j.ajhg.2007.10.012

Figure 3.

Figure 3

ROC Curves Comparing the Performance of the Single-Locus Analysis and the Ridge-Regression Methods

Each ROC curve represents the performance of one of the two regression methods when trying to detect association between the 26 SNPs of the CHI3L2 region and a simulated phenotype (solid line = single-locus regression; dashed line = ridge regression). Results are averaged among varying number (1–25) of functional loci.